United beat West Ham 2-1 in dramatic fashion last Sunday when Jesse Lingard scored late on before Mark Noble missed an injury-time penalty for the Hammers.
Under Ole Gunnar Solskjaer, United have laboured at times in the early stages of the season but they sit level at the top of the table with Chelsea and Liverpool on 13 points.
Cristiano Ronaldo will be out to continue his good goalscoring form after four goals in his first three games back at Old Trafford.
It is unlikely to be easy for United against a Villa side who look to be getting into their stride after an impressive 3-0 win over Everton last weekend.
Date, kick-off time and venue
Manchester United vs Aston Villa is scheduled for an 12:30pm BST kick-off at Old Trafford on Saturday.
Where to watch Man United vs Aston Villa
Saturday’s match will not be broadcast live on TV in the UK.
Man United vs Aston Villa team news
After making 11 changes in Wednesday’s Carabao Cup defeat against West Ham, Solskjaer will revert largely to the team that beat the Hammers in the Premier League last weekend.
Ronaldo will lead the line after having a week off, while the Raphael Varane, David De Gea, Bruno Fernandes and Harry Maguire will all return.
Man United vs Aston Villa prediction
United have flattered the deceive at times this season but they should have too much for a Villa side still finding its feet without Jack Grealish.
Man United 3-0 Aston Villa.
Head to head (h2h) history and results
(Premier League fixtures only)
Man United wins: 37
Villa wins: 3
Betting odds and tips
Man United to win: 4/11Draw: 15/4Aston Villa to win: 7/1